Spent a few hours yesterday at a beach called Neskowin, south of Lincoln City.
A native American name, don't know it it has anything to do with Confederations of Siletz Tribes who own the casino in Lincoln City. Haven't seen many natives if any in oh so many times i've been there, don't know if it's real or just a symbolic link between real owners and our perceived reality. Can't help here but to add that Siletz name resonates with the root sele (Selleck as in Tom Selleck or Sellers as in Peter Sellers, a quite common Hungarian last name with many variants and capital of Oregon, Salem or Soros are not far from it). I know for sure that i once caught a celebration at the casino when i saw Hungarian actors dressed as and pretending to be native Americans (known in the past as Indians).
It is the first beach i've ever been too in the US in August or September 1995 or 25 years ago. Veronica Mart took us there and we went to the beach and then we had a pick-Nick. Like yesterday, a small plane making a big noise passed very low on top of the beach and i was wearing European style swimwear that is not accepted here (two short) (not that you can swim much in Oregon, water temperature allows that only maybe once a year, in average). Name Nesko-win reminds of course of Nico and i remember i was intrigued she choose a pick-nick table in the parking lot that was next to restroom (i hear nowadays a commercial where a black guy pronounces the word restaurant very similar to restroom).
BTW recently searching through Hungarian actors databases i ran into a face that fits that of Veronica Mart. Sitting next to a a Hungarian renown actor, Gyula Szombathy who seems to be "Romanian pilot George Hârșovescu" as described in the post linked above. Here on right, slightly out of focus, don't know the name. Could be her.
Back at the beach. There was a whole continuous show unfolding all around us. Populated with now more like next in line (as opposed to top of the creme) Hungarian voice actors trying really hard to overcome the barriers of accent. But since all media is populated with them, who knows what "standard American English" is anymore. Don't know if newest style apparition, could have happened before and i forgot or didn't realize, next to us came two short blond women that seemed to be Japanese made to look like American, if that is possible. With a kid, they were syncing with everything we were doing. But i was too tired and much too dipped into nostalgia to pay attention to all details of the unfolding present. I first parked in a store spot, there was a warning for beach goers not to park in there. I went to the car several times to see what's happening, scenes unfolding like a Mexican wave every time. Later, as a spot freed i ended parking between two cars that in the end turned to belong to some Asians (read Japanese) that put up a show when we left.
And last but not least. On McMinville Ave there was a (tiny) house with an unusually shaped gate. There were of course some ropes and a couple of buoys hanging. I passed several times in front of it but planned to take a picture when i left, for obvious reasons. However when i left they were two guys in front of it, kinda staring at me.
At the end of the day Angela went to play at Chinook Winds nearby and i stayed in the car, listening music, surfing the web and then i fell asleep. But some people made a fire on the beach and there was so much smoke i could not stay in the car. I tried to start the fan but all i did was contaminate the new cabin filter that was still smelling hours later. So i moved at the top level in the new parking lot where you can hear the ocean and if you stand you can even see it. But that level is connected with a tunnel like passage with the room of the casino where they have the parties and base was so loud i could hear it from the car. Staring at the entrance of the parking lot with height limiters looking like a Shinto gate, like in the image with the fish above. Was thinking. They could have put it after the entrance of the first level, cause top level does not have height limit. But they put it in the street so it is visible as a symbol (google maps picture since 2018).
Right before Angela came a very attractive woman came and started and left with the car nearby.
I was pretty pissed last night when i drove back home (read sad). About most everything. But they stole that feeling from me too. At the red light camera at the intersection with 99. Angela doesn't let me to turn right on red at night when we're alone in the street at red light cameras, but this time there was a car behind me and another one going from right to left, with Asian women i think, all waiting (was there red in all directions?). After one minute of waiting i saw a flash, but kinda dim. Don't know for who it was, nobody was moving for about one minute before that. Then the light turned green and i started my right turn. They did that to me before, a flash in the night when i was going through one of these, for no reason. Malfunctioning? Mood changing, certainly. And creating a new fake branch of events. Bansenshukai.
Sunday, August 2, 2020
More on Lipid Bylayer
Following
Feel patient enough today to be able to read a scientific article?
"This thin, flexible, and potentially very fragile structure is all that stands between the interior of the cell and the environment." (Yeah, cells could not form organs if it wasn't for the extra-cellular matrix made of collagen, a very strong protein).
"Most books mention that membranes have a typical "lipid bilayer," but why lipids, why should it be a bilayer, and how was this basic structure determined? Although it is now generally taken for granted that membranes are based on the presence of a lipid bilayer, that was not always the case. Early experiments, often by physicists, led to the understanding that the cell membrane was lipid in nature. A key experiment using the Langmuir trough provided the basis for accepting that the membrane is a bilayer and laid the groundwork for the current model of membrane structure."
"Working in her kitchen, and with no formal training, she devised a simple apparatus to quantify the area covered by the oil film. Her apparatus was refined by Langmuir (1917) and is now generally referred to as a Langmuir trough (Figure 2), although it really should be a Pockels trough."
So that's it. Whole cellular biology science is based on this experiment done in the kitchen 100 years ago. Intrigued already?
Then see this.
In other words, CDC, first in front line of the battle with COVID thinks viruses are alive and eat protein. As for the formaldehyde part, i'm trying to think. Don't know of anything toxic inside a coronavirus.
Anyways this is not the purpose of this post. I'm still at the bylayer. Both cells and viruses are surrounded by a bylayer membrane. So when the viruses multiply inside a host cell in the end they have to "steal" a part of the cell's membrane to make it their own.
But then i realized i don't know how during cellular division (not all cells divide but most do) the "parent" cell shares its membrane to the two daughters.
What do i know. It looks like cells have muscles (and skeletons).
Actin and myosin. The muscle proteins inside cell that form the contractile ring that initiates the change of shape from spherical into two lobes and then the cell becomes two.
However virus progenies employ a different mechanism for generating their membrane. I was reading this article but did not fully understand how.
"Although membrane fusion for entry is a speciality of the enveloped viruses due to the presence of a lipid bilayer around them, HSV is capable of exploiting other routes of entry as well"
So we know how the virus enters the host cell. Membrane (lipid bylayer) fusion and/or endocytosis. But how is it released?
Apparently the virus emerges encapsulated by using parts of the Golgi network that turn into "secretory vesicles". But where the virus gets its spike proteins and how it breaks the cells membrane to escape?
I'm not getting to any conclusion yet and plan to read further in the immediate future but from what i read so far to me viruses are so fragile and the mechanisms of cell invasion, replication and building are so complicated it should take very little to brake them. Of course main motivation for writing this is frustration with a science and scientists who failed for such a long time to find something to disrupt them.
Feel patient enough today to be able to read a scientific article?
"This thin, flexible, and potentially very fragile structure is all that stands between the interior of the cell and the environment." (Yeah, cells could not form organs if it wasn't for the extra-cellular matrix made of collagen, a very strong protein).
"Most books mention that membranes have a typical "lipid bilayer," but why lipids, why should it be a bilayer, and how was this basic structure determined? Although it is now generally taken for granted that membranes are based on the presence of a lipid bilayer, that was not always the case. Early experiments, often by physicists, led to the understanding that the cell membrane was lipid in nature. A key experiment using the Langmuir trough provided the basis for accepting that the membrane is a bilayer and laid the groundwork for the current model of membrane structure."
"Working in her kitchen, and with no formal training, she devised a simple apparatus to quantify the area covered by the oil film. Her apparatus was refined by Langmuir (1917) and is now generally referred to as a Langmuir trough (Figure 2), although it really should be a Pockels trough."
So that's it. Whole cellular biology science is based on this experiment done in the kitchen 100 years ago. Intrigued already?
Then see this.
In other words, CDC, first in front line of the battle with COVID thinks viruses are alive and eat protein. As for the formaldehyde part, i'm trying to think. Don't know of anything toxic inside a coronavirus.
Anyways this is not the purpose of this post. I'm still at the bylayer. Both cells and viruses are surrounded by a bylayer membrane. So when the viruses multiply inside a host cell in the end they have to "steal" a part of the cell's membrane to make it their own.
But then i realized i don't know how during cellular division (not all cells divide but most do) the "parent" cell shares its membrane to the two daughters.
What do i know. It looks like cells have muscles (and skeletons).
Actin and myosin. The muscle proteins inside cell that form the contractile ring that initiates the change of shape from spherical into two lobes and then the cell becomes two.
However virus progenies employ a different mechanism for generating their membrane. I was reading this article but did not fully understand how.
"Although membrane fusion for entry is a speciality of the enveloped viruses due to the presence of a lipid bilayer around them, HSV is capable of exploiting other routes of entry as well"
So we know how the virus enters the host cell. Membrane (lipid bylayer) fusion and/or endocytosis. But how is it released?
Apparently the virus emerges encapsulated by using parts of the Golgi network that turn into "secretory vesicles". But where the virus gets its spike proteins and how it breaks the cells membrane to escape?
I'm not getting to any conclusion yet and plan to read further in the immediate future but from what i read so far to me viruses are so fragile and the mechanisms of cell invasion, replication and building are so complicated it should take very little to brake them. Of course main motivation for writing this is frustration with a science and scientists who failed for such a long time to find something to disrupt them.